- CODEN : IAJPBB
- issn 2349-7750
TITLE:
OVARIAN STRUCTURAL DAMAGE: EFFECTS OF MONO SODIUM GLUTAMATE IN EXPERIMENTAL ALBINO FEMALE RATS
AUTHORS:
Piriha abbasi, Zaheer Ahmed, Raima Kalhorho, Sana Kashif4, Mozna Talpur, Muhammad Ishaque
ABSTRACT:
Mono sodium glutamate is a food preservative but it is prevailing concept that it has some harmful effects on human body. This current experiment was conducted in animal House at Agricultural University, Tandojam, Sindh, Pakistan on two groups of female rats. Each group consisted of 10 rats, group A was given normal diet but kept free from MSG to serve as control and group B was administered MSG at a dose of 0.08mg/gm for 4 weeks. Histology of ovaries was seen under microscope after making sections in anatomy department using hematoxylin and eosin stains .Group B showed significant disturbance in ovarian histology with thecal hypertrophy in 8 rats, hemorrhage in 7 follicular destruction and vacuolization each in 4 while 8 rats were found with loss of basement membrane as compared to normal histology of the normal group A. Conclusion: Mono sodium glutamate is responsible for structural damage to the ovaries of experimental rats Key Words: MSG, Ovaries, hematoxylin, eosin, albino rats
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Approved Journal
NLM ID:101711216 [Serial]
Included in EuroPub database
ICV 2015 - 61.16
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S.J Impact Factor:7.157
cosmos Impact Factor:4.153
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IP Indexing Impact Factor: 2.76
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