Dr. Faiza Shoukat, Dr. Muhammad Imran, Dr. Sara Mateen
Objective: The objective of this research was to investigate and identify the T2DM patient’s cognitive dysfunction along with OSAS (Obstructive Sleep Apnea Syndrome); we also aimed to analyze related features as well. Methods: This research was carried out on a total of 115 T2DM patients at Mayo Hospital, Lahore (October 2017 to June 2018). The patients were divided into two groups of OSAS (83) and non-OSAS (32) groups. Physical assessment of every patient was carried out. We also evaluated the levels of Nocturnal lowest saturation of pulse oxygen (LSPO2), Apnea-hypopnea index (AHI) and simple mental state examination scale (MMSE). Results: In the patients diagnosed with diabetes, OSAS have reduced glycated haemoglobin, thrombocytocrit, platelet count, lowest mean arterial oxygen and MMSE score than non-OSAS patients; glycemic control and cognitive dysfunction state of patients have an association with diabetes duration. Glycemic control is poor along with prolonged diabetes duration which makes the cognitive dysfunction even obvious. Conclusion: T2DM patients with prolonged diabetic duration along with OSAS; the glycemic control tends to be poor which easily causes cognitive dysfunction. Meanwhile, blood system coagulation in the patients of OSAS along with diabetes bear some impact. Keywords: T2DM, Diabetes, Lowest Saturation of Pulse Oxygen (LSPO2), Apnea-Hypopnea Index (AHI) and Simple Mental State Examination Scale (MMSE) and Platelet.