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TITLE:

A RESEARCH STUDY ON THE OCCURRENCE OF ANTI HCV ANTIBODIES IN BLOOD DONORS

AUTHORS:

Um-e-Salma, Rida Jamil, Asia Akram

ABSTRACT:

Objective: The objective of this study is to evaluate the prevalence of anti-hepatitis C virus antibodies in the donors of blood. Study Design: The study was a retroactive work conducted Blood Bank of Jinnah Hospital, Lahore. This study covered a duration of complete 1 year after the start of screening of hepatitis C virus. The analysis of the percentages of the occurrence carried out in this study. Study Setting: The collection of the data carried out from different other hospitals, departments of the same hospital and other branches of the hospital. EIA was in use for the initial samples of the serum in our institute. A sum of 166,183 donors of 1st time or standby blood donors having the age from 18 to 60 years who gave their blood in emergency mobile sessions or in various blood banks were the part of this research work. All the donors of blood who verified non-reactive on EIA were not the part of this case study. The evaluation of the occurrence of the hepatitis C virus infections in the donors of blood. Results: Total 4.450% blood donors primarily tested sensitive; out of these 0.360 % were not correctly on the screening conducted firstly. Advance testing with the help of EIA showed the exact occurrence of hepatitis C virus in the donors at 4.10%. Conclusions: The service for the transfusion of the blood initiated the screening for hepatitis C virus in May 2016 and the occurrence of hepatitis C virus amongst TTIs (Transfusion Transmitted Infections) for the Punjab was very high. It was two times greater than the occurrence of HBV infection and many thousand times greater than the infection of HIV. There is a requirement of careful & total coverage of screening to tackle this terrible situation. The review of the methodology for testing is also very necessary. Key Words: Blood, transfusion, donor, HCV, infection, HIV, HBV, measure, EIA, screening, terrible, blood banks.

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