- CODEN : IAJPBB
- issn 2349-7750
TITLE:
ANTIMICROBIAL &SYNERGISTIC ACTIVITY OF ANTIBIOTICS AGAINST COMMON CLINICAL ISOLATES.
AUTHORS:
Zehra Ashraf, Mirza Tasawer Baig , Waseem Abbas ⁕, Ifrah Athar, Nimra Waheed
ABSTRACT:
Object: This experiment was carried out to check the anti-bacterial & synergistic effect of different antibiotics on gram negative (E-coli) & gram positive (S-aureus) bacteria. Method: Basically, the whole experiment was carried out in two parts, 1st by looking for the individual effect of anti-bacterial drugs and 2nd by evaluating the synergistic effect taking Amoxicillin (50µg) as standard. Hundred bacterial samples taken from the laboratory were collected from different sites of infected person. The experiment was carried out by disc diffusion method & by considering CLSI standards to check the resistance result. Result: We have observed that the male patients are more prone to infections caused by E-coli. The greater occurrence of E. coli &S.aureus was obtained from Respiratory Tract. E. coli & S.aureus showed 100 % resistance against Cefotaxime. In S.aureus isolates the most effective therapy was Amoxicillin-Ciprofloxacin & in E.coli isolates best effective therapy was Amoxicillin-Gentamycin. Key words: Anti-bacterial activity, Disc Diffusion Method, Synergy, Zones.
FULL TEXT
Approved Journal
NLM ID:101711216 [Serial]
Included in EuroPub database
ICV 2015 - 61.16
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S.J Impact Factor:7.157
cosmos Impact Factor:4.153
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