::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

EVALUATION OF DIFFERENT PROGNOSTIC FACTORS WHICH REGULATE THE OUTCOME BY SURGICAL REPAIRING OF VESICOVAGINAL FISTULA

AUTHORS:

Dr Shahid Latif, Dr Muhammad Awais, Dr Maria Khalid

ABSTRACT:

Introduction: Vesicovaginal fistula (VVF), communal among urogenital fistulas, is regarded as obstetric morbidity expected to consequence more than two million women worldwide. The rate of VVF is lower in industrial countries where it happens as an obstacle of pelvic surgeries or radiation therapy. Objective: Evaluation of different prognostic factors which regulate the outcome by surgical repairing of vesicovaginal fistula. Methods: In Jinnah Hospital Lahore, a reflective survey was held which is composed of the data relevant to victims of vesicovaginal fistula repair during February 2015 to July 2018. The record was examined through SPSS 22 software defining odds ratio having 95% confidence interval. Results: Data of 640 victims was investigated with success rate of 558 (87.2%) cases. This investigation revealed that reappearance of disease was expressively linked to multiplicity (9-fold recurrence risk), pre-operative size (10- fold reappearance risk for fistula > 2cm equated to <1cm), secondary repair (5-fold risk) and extent of the fistula (3- fold risk). Insinuation of flap and tardy rebuilding (between 6 weeks and 1 year) was linked to effective surgical results. Aetiology, age, parity, repairing route and fistula location were not substantial (p>0.05 each0 prognostic factors for reappearance. Conclusion: For effective restoration of vesicovaginal fistula cautious determination of several factors is needed comprising number, size, previous efforts for restoration and interval of fistula. Keywords: Prognostic factors, Recurrence, Surgical repair, Vesicovaginal fistula.