- CODEN : IAJPBB
- issn 2349-7750
TITLE:
ALTERED HAEMATOLOGICAL INDICES AMONG PATIENTS WITH TYPHOID PRESENTING TO A TERTIARY CARE HOPSITAL
AUTHORS:
Shaista Ahmed, Firasat Waqar, Aisha Javed, Afshan Siddiqui, Sadia Iqbal & Muhammad Muneeb, Aatir H. Rajput, Abid Ali, Anam Shaikh & Tahir Hanif
ABSTRACT:
Objective: To study the altered hematological indices among patients presenting with typhoid to a tertiary care hospital. Study Design: Descriptive Study Design Place & Duration: Study conducted at Abbasi Shaheed Hospital, Karachi from July 2, 2018 to Oct 26, 2018. Methodology: This hospital based descriptive study, was conducted upon a sample of 377 consecutive patients presenting with typhoid (diagnosis confirmed on the basis of Widal test or Typhidot test), at Abbasi Shaheed Hospital, Karachi. After taking written informed consent, data was collected using a structured interview based proforma comprised of inquiries about the respondent’s bio data, socio demographic details, and hematological indices (CBC, peripheral smear, electrolyte levels, reticulocyte count and prothrombin time) obtained from laboratory records. The study was carried out from July 2, 2018 to October 26, 2018. Data obtained was analyzed using SPSS version 21.0 and MS. Excel 2013. Results: Among of 377 respondents, an approximate 3/5th of them were females (n = 226) and an approximate 2/5th belonged to the male gender (n = 111) with an estimated mean age (29.4 years) and a mean hospital stay of 8 days for males and 5 days for females. The most commonly altered hematological indices observed were; anemia (48.54%), thrombocytopenia (42.71%), elevated prothrombin time (31.8%), leucocytosis (8.2%) and leucopenia (5%). No mortality was reported and all the patients were discharged healthily after treatment. Conclusion: Hematological indices are significantly altered in typhoid fever and knowledge regarding these changes can help not only in the diagnosis but management of the condition as well. The changes however are short lived and show positive responsive upon administration of relevant antimicrobial treatment. Keywords: Typhoid Fever, Enteric Fever, Salmonella Typhi, Hematological Indices & Hematological Changes
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Approved Journal
NLM ID:101711216 [Serial]
Included in EuroPub database
ICV 2015 - 61.16
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S.J Impact Factor:7.157
cosmos Impact Factor:4.153
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IP Indexing Impact Factor: 2.76
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