::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

STUDY TO KNOW THE IMPORTANCE OF TRIPLE PHASE COMPUTED TOMOGRAPHY RESULTS FOR HEPATIC LESIONS EVALUATION

AUTHORS:

Dr. Maham Munir Awan, Dr. Asra Yasin, Dr. Umama Saeed, Dr. Hira Bushra, Dr. Umaima Majeed, Dr. Mustafa Ali Siddiqui

ABSTRACT:

Due to liver amounts of blood supply through the hepatic artery and portal vein, digestion and detoxification it is prone to various diseases including benign and malignant. Objective: To examine the characteristics of various liver lesions by using triple phase CT as diagnostic modality, to distinguish from benign malignant hepatic lesions and to calculate the effectiveness by associating triple-phase CT findings with histopathological, clinical or postoperative findings. Study Design: A cross-sectional study. Place and duration: In the Radiology department of Chaudhry Pervaiz Elahi Institute of Cardiology (CPEIC), Multan for one year duration from October 2017 to October 2018. Methods: A total of 100 patients were included in this cross-sectional study in the Department of Radiology. A triple-phase CECT was performed in all patients and their accuracy, sensitivity and specificity were calculated. Results: Triple phase CT is an excellent diagnostic method for the characterization and better evaluation of hepatic masses with 91.3% sensitivity, 97.8% specificity, 91.3% PPV and 97.3% PPV. 8% (p value <0.001, kappa value 0.847). Malignant hepatic lesions were 93%, 93.3%, 92.5%, PPV and NPV, 94.9% and 90.2%, respectively, by triple-phase CT, respectively. Conclusion: High-precision triple-phase CT useful for reliable diagnosis of liver damage. It has an indispensable role in the characterization, evaluation and differentiation of benign and malignant liver lesions that help to guide the appropriate treatment plan with adequate surgical classification. It is also useful to reach a diagnosis of primary malignancy in multiple hepatic metastases of unknown primary origin. Key words: benign, malignant, hepatic masses, arterial phase, portal venous phase, delayed phase, triple phase CT.