::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

COMPARATIVE RESEARCH TO ASSESS THE LEVEL OF C-REACTIVE PROTEIN (CRP) AMONG SMOKERS AND NON-SMOKERS DIAGNOSED WITH CHRONIC PERIODONTITIS

AUTHORS:

Dr. Aneela Tariq, Dr. Saad Asim, Dr. Tayyaba Nasir

ABSTRACT:

Objective: This research aimed at the comparison of smoking effects on the CRP (C-Reactive Protein) levels among chronic periodontal disease patients. The effect and response of periodontal management on the level of CRP was also observed while comparing Smokers and Non-Smokers. Patients and Methods: This research was carried out at Allied Hospital, Faisalabad from October 2017 to May 2018 on a total of 100 chronic periodontitis patients. We verified the smoking history and accordingly classified the patients in two groups respectively Group – A as Smokers and Group – B as Non-smokers. Every patient was also assessed for periodontal assessment for level of CRP through blood sampling. Every patient received the same management of chronic periodontitis that is calculus removal through mechanical way with a prescription of mouth rinses and antimicrobials. Blood samples and periodontal assessment was again repeated at an interval of three months to verify the level of CRP for possible variation. Results: We observed that at baseline, level of CRP was increased in Smokers (Group – A) than Non-Smokers (Group – B). After being treated the outcomes of second assessment was improved after treatment about periodontal health. There was a significant decrease in the Mean level of CRP of both smokers and non-smokers. Conclusion: There is a significant effect of Chronic periodontitis on the levels of CRP. Chronic periodontitis may increase an individual’s inflammatory burden which can be changed through suitable treatment. Adverse smoking effects do not affect such response. Keywords: Smokers, Non-Smokers, CRP (C-Reactive Protein), Health, Chronic Periodontitis and Periodontal.