::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

A REVIEW ON ALZHEIMER’S DISEASE

AUTHORS:

N.Jyothi, B.Ramya,G.Sai kumar,G.Navya,1N.Bramarambha, Sumaiya maisara, Dr.K. RajeswarDutt, Dr. K.N.V Rao, Dr.K.Bali reddy, N.Shiva krishna,K.Nava Jyothi.

ABSTRACT:

Alzheimer’s disease is an irreversible, progressive brain disease that slowly destroys memory and thinking skills. The prevalence is 3% for persons 65-74 years old, 19% for those 75-84 years pld and 47% for those over 85 years old. Ad is mainly clinically manifested with dementia. The etiology of AD includes cholinergic, amyloid, tau hypothesis. Pathogenesis of AD involves the apperance of extra cellular beta-amyloid plaques and intra cellular neurofibrillary tangles. Drugs mainly includes Anticholinesterases. The recent reserchers using various animal modles are promising a definite and complete treatment for AD in coming years. Above everything it is the love and affection of the family that is what required for AD patient. Alzheimer’s patients are exactly like any other patients in that they need plenty of care, support, patience, and love.AD patients show increased level of miRNAs are considered promising non-invasive candidates for AD diagnosis and prognosis.