Dr. Muhammad Khurram Shahzad*, Dr. Ayesha Ambreen**, Dr. Javed Iqbal***
Objective: Comparison between intralesional vitamin D3 therapy and cryotherapy in the treatment of plantar warts. Methods: A total of 128 patients aged between 18-35 years, having plantar warts, were randomly assigned into groups A and B (n=64, in each group. Patients in group A were given intralesional injection of vitamin D3 in each wart at 4 week interval for a maximum of 2 sessions. Patients in group B were given cryotherapy at weekly intervals for a maximum of 5 sessions. Patients were followed at 2nd, 3rd and 6th week, and both therapies were compared. Results: Out of 128 patients, 69 (53.91%) were males and 59 (46.09%) were females with male to female ratio of 1.2:1. The mean efficacy of intralesional vitamin D3 therapy was seen in 85.63% patients, while efficacy of cryotherapy was seen in 62.61% patients (p=0.002). Conclusion: This studyconcluded that intralesional vitamin D3 has more efficacy than cryotherapy in the treatment of plantar warts. Keywords: plantar warts, vitamin D3, intralesional cryotherapy.