Dr Momina Muqadus, Dr Aaisha Qadir, Dr Iqra Maqbool
Objective: To determine commonest SAAG “serum-ascites albumin gradient” value in cirrhotic disease patients having esophageal varices and to evaluate serum albumin and serum ascites values. Study Design: A cross sectional study. Place and Duration: In the East Medical Ward of Mayo Hospital Lahore for one year duration from July 2017 to July 2018. Methods: This section was performed on hundred patients of cirrhosis with ascites to calculate the SAAG level in ascitic and serum fluid, SAAG value (≥ 1.1 g / dl) was examined and high SAAG value ≥ 1.1 g / dl when <1.1 g / dl to classify the esophagus varices SAAG under. All patients were done with upper GI endoscopy. Results: Of the hundred patients, 62 were male and 38 were female. The SAAG was 1.099 ± 0.62. In 87 patients, Esophageal varices (EV) were noted and were not present in thirteen subjects. The esophageal varices grading, SAAG degree (p <0.01) and correlation coefficient r = 0.56 (p <0.01) stressed significant correlation. Using the ROC curve, the SAAG value, ie, 1.64 ± 0.014 g / dl, was an accurate indication of the EV onset; for the highest predictive value, the cut-off points were 96% negative and 98% positive. Conclusion: In cirrhosis patients having ascites, the onset of EV is only related with SAAG, and the EV size is associated with SAAG degree. SAAG value ≥ 1.65 ± 0.014 g / dl is helpful tool in predicting the onset of EV in subjects having cirrhosis with ascites. key words: Esophageal varices, SAAG, cirrhosis, portal hypertension.