::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

STUDY TO KNOW THE NON-NEOPLASTIC SKELETAL DISEASE CLINICAL AND PATHOLOGICAL PATTERN

AUTHORS:

Dr Yusra Nayab Khan, Dr Sana Tariq, Dr Shumaila Najeeb Piracha

ABSTRACT:

Objective: Non-neoplastic skeletal lesions, especially tuberculous and pyogenic osteomyelitis, form an important group of joint and bone diseases. Study Design: A descriptive cross-sectional study. Place and Duration: In the Pathology Department of Services Hospital Lahore for two year duration from June 2016 to June 2018. Methods: After detailed documentation of clinical account, bone biopsies of 172 patients with variable clinical symptoms under microscope were reviewed. Results: There were 117 male and 55 female (E: K = 2.2: 1). The maximum number of patients with a mean age range of 11-20 years (n = 51) and 49.5 ± 6 years was the mean age. A wide range of clinical lesions including inflammatory (n = 92), infectious (n = 53), cysts (n = 07) and synovial (n = 20) diseases were observed. Non-specific inflammation (n = 52) followed by pyogenic infections (n = 32) and tuberculosis osteomyelitis (n =) formed the main group. Conclusion: Neoplastic bone diseases are very diverse. Men are affected twice by women and most diseases occur in young age groups. Non-specific inflammation and tuberculosis osteomyelitis are the main group. Lower extremities are commonly affected. Key words: non-neoplastic skeletal disease, tuberculosis osteomyelitis, synovial disease.