::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

AN ASSOCIATION BETWEEN ASTHMA AND VITAMIN D: A PROSPECTIVE STUDY IN A VICTORIA HOSPITAL BAHWALPUR

AUTHORS:

Dr. Maria Nazir, Dr. Erisha Komal, Dr. Aisha Saddiqui

ABSTRACT:

Introduction- Due prolonged inflammation in airways, one of the most common disease occur which is called asthma. Mast granulations modulated by Vitamin D and raised level of IgE are normally the common causes of asthma. Materials & Methods- For this study 50 patients were selected from Chest Medicine unit in BVH which were suffering in asthma and at start their Vitamin D level, IgE level, blood eosinophil count and sputum was investigated and in all of them Sputum eosinophil count mean was very high in the 31(10.13 3.8). Likewise raised level of IgE was seen and also the eosinophils level in the serum. Results- Most of the patients e.g. 14 who were found to be deficient in Vit I, 45.2% were suffering in severe asthma while 9 of them i.e. 29% were suffering in moderate asthma. Intermittent asthma was seen in 2 (6.5%) and mild in 6 (19.4%). 21 patients who were deficient in Vitamin D also had Atopy and 61.6 3.7 was the mean FEVI % in them. Conclusion- It was concluded that early detection of deficiency of Vitamin D in patients can be very helpful in assessing the asthma, its effective treatment and it’s the severity of asthma in early stages. With this hospitalization and cost can also be reduced