Dr Nawal Yousuf , Dr. Muhammad Hasnain Aslam, Dr Khalida Begum
Background and objective: Infective endocarditis (IE) is an infection of the cardiac valves or mural endocardium caused by bacteria and fungi producing a wide variety of systemic signs. The basic aim of the study is to find and analyze the Microbiological and clinical profile of infective endocarditis patients of local population of Pakistan. Methodology of the study: This descriptive study was conducted at Nishtar Hospital Multan during March 2019 to November 2019. This was a prospective cohort study performed at the Clinical Laboratory (microbiology section) and cardiothoracic surgery of the hospitals. We identified suspected IE patients from samples submitted at the clinical lab: all blood and relevant tissue samples (cardiac vegetation, cardiac valves, valvular abscess etc.) that were received with history suggestive of endocarditis were enrolled and verbal consent obtained for it. ResultsDuring the study period, 100 patients with clinical diagnosis of IE were prospectively enrolled (table 01). Mean age of patients was 34.84 years with 72.1% being males. Adult representation was 84.6% and 15.4% were below 16 years. Using the MoDC 65.4% (n = 50) were identified as “definite cases of infective endocarditis” rest fell in the “possible case”. Conclusion: It is concluded that Infective endocarditis remains a constant source of menace in medical practice, with associated morbidity and mortality.