::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

LEVELS OF LIPID PEROXIDATION IN BREAST CANCER PATIENTS RECEIVING RADIOTHERAPY

AUTHORS:

Dr Fria Maqsood, Dr Amna Rabbani

ABSTRACT:

Background and objectives: Cancer is a group of diseases characterized by uncontrolled growth and spread of abnormal cells. The aim objective of this study is to find the level of lipid peroxidation in breast cancer patients who receives cancer therapies. Material and Methods: This descriptive cross sectional study was conducted at BHU, Bahishti with the collaboration of Jinnah Hospital, Lahore during March 2019 to January 2020. Those breast cancer patients who receiving radiotherapy, chemotherapy and adjuvant radiotherapy were selected to study the lipid peroxidation status in the diseased condition. Results: The data explains the levels of MDA in breast cancer females. The data suggest that lipid peroxidation is increases in breast cancer. The reason is due to high damage of membrane and lipid peroxidation poducts. Conclusion: By reducing oxidative stress, antioxidants counteract the effects of chemotherapy-induced oxidative stress on the cell cycle and enhance the cytotoxicity of antineoplastic agents.