::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

STUDY TO IDENTIFY EXISTENCE OF ASSOCIATION BETWEEN FAMILY HISTORY OF DIABETES AND SUSPECTED CASES

AUTHORS:

Dr Fawad Ahmed, Dr Aliya Latif, Dr Afifa Chaudhary

ABSTRACT:

Background: Type-II Diabetes is a major global health risk and is often associated with genetic inheritance of diabetes. Objectives: The aim of the study was to identify whether an association exists between family history of diabetes and suspected cases of diabetes. Study Design: Cross Sectional Study. Place and Duration: This study was conducted in screening camps of Services hospital Lahore for the duration of one year from December, 2018 to November, 2019. Methodology: Total number of 2000 persons were included in the screening process. People with BSR≥200mg/dl were labelled screened positive for diabetes. People with BSR<200mg/dl were categorized as Normal. Family history of any family member having diabetes was taken for all participants. The members of the family only included immediate blood relations like mother, father, brother, sister and grandparents. Data was entered in SPSS 20 for analysis. Frequency distribution and percentage were calculated for age, gender, screening for diabetes and family history of diabetes. Chi square was used as a test of significance for association between family history and diabetes. Results: People aged 25 and above were screened for diabetes. 104 people were screened positive for diabetes. 67.9% were females and 32.1% were males. Mean age was 43±12.61 years. In Normal category, 90.3% people had no family history of diabetes in their family while 9.7% reported positive family history. In screened positive for diabetes category, 64.7% people did not report any history of diabetes in their family where as 35.3% reported having positive family history. The association between diabetes and family history was found to be statistically significant. Conclusion: Risk of diabetes is associated with a positive family history of diabetes. Screening for early detection should be performed regularly for people with positive genetic risk of diabetes to ensure prevention and control of complications.