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TITLE:

TO DETERMINE ORAL LICHEN PLANUS FREQUENCY IN NON-INSULIN DEPENDENT DIABETIC PATIENTS

AUTHORS:

Dr Afifa Chaudhary, Dr Fawad Ahmed, Dr Aliya Latif

ABSTRACT:

The association between lichen planus (LP) and diabetes mellitus, especially oral lichen planus, has been the subject of many studies, but the result is controversial. In diabetes mellitus, 1.6% to 85% is the oral LP frequency reported frequency. Objective: To govern the oral lichen planus incidence compared to normal subjects with non-insulin dependent diabetes mellitus. Study Design: An Observational Study. Place and Duration: In the dermatology outpatient department of Lahore General Hospital for one year duration from March 2018 to March 2019. Methods: NIDDM cases with suspected oral lichen planus lesions between 40 and 70 years that met the selection criteria for both sexes were recorded. After obtaining informed consent, the recruited patients were examined after a detailed history and biopsy and histopathology were performed. Any relevant research was carried out as needed. Equal age and sex matched controls for oral LP were also examined. Results: Of the 49 (57%) females and 37 (43%) males from total of 86 patients, aged between forty to seventy years, with of 51.3 years mean age. There were 3 age groups, i.e. forty to fifty years, fifty to sixty years and above sixty year. Eight (6.9%) of these patients had histopathologically confirmed oral lichen planus (P <0.05). The disease was confirmed histopathologically in only one (1.2%) of the control group. There were 5 women (62.5%) and 3 men (37.5%). Oral mucosa was included in 7 patients (87.5%). Conclusion: In this analysis, it can be determined that oral Lichen Planus has noteworthy relationship with NIDDM as paralleled to the healthy subjects. Keywords: oral lichen planus, NIDDM, lichen planus.

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