::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

INCIDENCE OF DUODENAL ULCER PERFORATION CAUSED BY HELICOBACTER PYLORI INFECTION

AUTHORS:

Dr Amna Manzoor, Dr Muhammad Umar Arif, Dr Unzurna Gull Khan

ABSTRACT:

Purpose: To know the frequency of H. Pylori infection causing DU perforation. Place of study: This study is a descriptive study conducted at the Medicine Unit I and Surgical Unit II of Services Hospital Lahore for Six months duration from July 2019 to December 2019. Material and methods: We included all patients with DU perforation. Patients with pre-pyloric ulcer, gastric ulcer and perforation and perforated gastric malignancies were excluded from the study. Results: 116 patients with perforated duodenal ulcer were observed during the study. 92 of them are men and 24 women. In our study, we found that perforated DU is more common in the 30-50 age group. Conclusion: H. Pylori, stress, smoking and abuse of NSAIDs are factors causing perforation of a duodenal ulcer. We suggest conducting a randomized controlled trial to assess those factors that cause perforation of duodenal ulcers in our world. Key words: Helicobacter Pylori, DU perforation, infection.