::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

RATE OF PREVALENCE OF VARIOUS REASONS OF PANCYTOPENIA AND DETECTION OF DEFICIENCY OF VITAMIN-B12 AMONG PATIENTS

AUTHORS:

Samun Manzoor, Ch. Noman, Qasim Ali

ABSTRACT:

Objectives: To determine the rate of prevalence of various causes for pancytopenia and to identify the frequency of deficiency of Vitamin-B12 in the patients suffering from pancytopenia. Methodology: This prospective research work carried out in Rural Health Center Roda, Khushab and the duration of this study was from April 2019 to September of 2019. We included 88 patients after complete examination and getting detailed history. We recorded all the information on a Performa. We interpreted the outcomes of aspiration and trephine biopsies in light of history, medical assessments and findings of peripheral blood. Results: Among 88 patients suffering from pancytopenia, majority of the patients (40.9%) were identified with MA (Megaloblastic Anemia), out of which 77.77% patients were present with deficiency of Vitamin-B12. Aplastic anemia (AA) was present in 31.88% (n: 28) patients followed by some other less frequent reasons. Conclusion: In majority of the patients, there was presence of Megaloblastic Anemia. All these patients were suffering from pancytopenia on initial assessments and most of these patients were present with the Vitamin-B deficiency. KEY WORDS: Aplastic Anemia, Pancytopenia, Megaloblastic Anemia, Aplastic, Vitamin B12.