::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

A CASE STUDY TO DETERMINE THE LIPID PROFILE IN PAKISTANI POPULATION

AUTHORS:

Qasim Ali, Ch. Noman, Samun Manzoor

ABSTRACT:

Introduction: Diabetes mellitus is a metabolic disease caused by the rise in blood sugar level as a results of insulin deficiency or insulin resistance. Objectives: The objective of the study is to examine the lipid profile in type-2 diabetic patients among local population of Pakistan. Methodology: This cross-sectional study was conducted in Rural Health Center Roda, Khushab and the duration of this study was from November 2018 to April 2019. The data was collected from 100 diabetic patients. Patients from both genders, age range from 38 to 68 years was selected for this study. The pre devised proforma recommend subject’s demography, and clinical portrait which is done by researcher. By using Randox kit, fasting plasma glucose, serum total cholesterol, high-density lipoproteins cholesterol, low-density lipoproteins cholesterol and triglycerides was measured. Results: The information was collected from 100 patients. The demographic values show that there's a relation between diabetes and hyperlipidemia among the population of Pakistan. The worth of HbA1C is 5.79 ± 0.52 in diabetic patients as compared to normal group. We found direct correlation between harshness of diabetic retinopathy with baseline sugar factor, HbA1c, serum low-density lipoproteins cholesterol, total cholesterol and triglycerides, although age and period of Diabetes mellitus showed slightly direct correlation with harshness of diabetes. Conclusion: In the conclusion of our study, secure direct correlation was form between serum total cholesterol, triglycerides, low-density lipoproteins cholesterol with both baseline sugar factor and HbA1c, at the same time high-density lipoproteins cholesterol showed feeble indirect correlation with both baseline sugar factor and HbA1c. KEYWORDS: Diabetes Mellitus, Insulin Deficiency, Metabolic Disease, Triglycerides, Fasting Plasma Glucose.