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A STUDY TO DETERMINE THE PREGNANCY OUTCOME IN ADVANCED MATERNAL AGE

Dr. Sofia Amber Malik

Objective: To investigate obstetric outcomes in the women with advanced maternal age. Study Design: A retrospective cohort study. Place and Duration: In the Obstetrics and Gynaecology department of Alzahra Pvt Hospital, Sharjah for one year duration from May 2018 to May 2019. Methods: 585 obstetric features of women aged forty years and above who delivered were compared from the hospital records of 1816 young mothers with age range of 20 to 29 years. The relationships between some obstetric variables and maternal age were measured using the contingency X2 test or Fisher's two-tailed test. Results: Advanced maternal age multiparous and primiparous were more probable to done with cesarean delivery than their younger counterparts (RR=2.85, 38.5% vs 13.5%, Less than 0.05 P) and RR=1.76, 16.1% vs 9.1%, Less than 0.05 P). The incidence of preeclampsia / eclampsia was higher in multiparous women in the advanced age group (2.4% versus 0.7%, p <0.01, RR = 4); fetal distress (RR = 2.69, 3.5% versus 1.3%, Less than 0.01 P value); antepartum haemorrhage (RR = 2.25, 1.8% vs. 0.8%, Less than 0.01 P value); postpartum haemorrhage (RR = 2, 1.2% vs. 2.4%; Less than 0.05 P value); preterm labour (RR = 1.30, 12% vs. 9.2%, Less than 0.05 P value); fetal death (RR = 2.18, 3.5% vs. 1.6%, Less than 0.05 P value); low birth weight (RR = 1.42, 11% vs. 7.7%, Less than 0.05 P value); low Apgar scores 1 min and 5 min; admission to the neonatal special care unit (RR = 1.38, 14.1% and 10.2%, Less than 0.05 P value) and perinatal mortality (RR = 2.18, 3.5 vs. 1.6, Less than 0.05 P value) was also high in advanced maternal age women. Conclusion: The results show that the most common adverse perinatal consequences risk with advanced maternal age is related indirectly to age-related obstetric complications risk. The risk of caesarean section increases with progressive maternal age. The high risk of intrapartum and antepartum complications was related to adverse perinatal outcome in elderly multiparous women. Keywords: pregnancy, increase in maternal age, perinatal outcome.

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