ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

AN ASSESSMENT OF SERUM FIBRINOGEN LEVELS IN PATIENT OF ACUTE STROKE

Dr. Tahira Jabeen, Dr. Shaheena Nawab, Dr. Muhammad Naveed Abbas

Objective: To assess the serum fibrinogen levels in patient of stroke presenting at BVH Bahawalpur. Material and methods: This cross-sectional study was conducted at Department of Pathology, Quaid-e-Azam Medical College/BVH, Bahawalpur from September 2018 to March 2019 over the period of 6 months. Total 50 patients with first-ever stroke admitted within 24 h after stroke onset either male or female were selected for this study. Serum fibrinogen levels were assessed in selected patients. Results: A total of 50 patients of stroke were enrolled and studied. Thirty (60%) cases reported ischemic stroke while hemorrhagic stroke was observed in 20 (40%) cases. Thirteen out of 50 (26%) patients were in the age group of 31-40 years; with age distribution of rest of the participants being relatively evenly distributed. Males (29, 58%) outnumbered females (21, 42%). Conclusion: In conclusion, we report significantly higher than normal mean fibrinogen levels in ischemic and hemorrhagic stroke and fibrinogen levels increased with increasing infarct volume and the correlation between infarct volume and fibrinogen levels being significant in ischemic stroke. In both the groups, the fibrinogen levels in patients who died was insignificantly higher as compared to patients who survived. Limited mortality numbers probably didn’t allow the observations of present study to reach the level of significance, which prompts us to recommend similar study with higher numbers. Key Words: Hemorrhagic stroke, Ischemic stroke, Plasma fibrinogen level

FULL TEXT