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TITLE:

ASSESSMENT OF QUALITY OF LIFE IN PATIENTS WITH METASTATIC BREASTCANCER AND ITS PHARMACEUTICAL MANAGEMENT IN TERTIARY CARE HOSPITAL: A PROSPECTIVE OBSERVATIONAL STUDY

AUTHORS:

Dr. Satish Kumar A., Yangalasetty Sravani*., Kadiyala Tejaswini Vinaya., Medarametla Poornima., Dr. N.V.Ramarao., Prof. Ramarao Nadendla

ABSTRACT:

Instead of the progression that has been made in diagnosis and treatment of early stage breast cancer a significant proportion of patients still go on to develop incurable metastatic breast cancer that has spread to distant sites of body like lung ,liver, bone, brain. Patients may experience limitations in their daily activities and reduction in their quality of life (QOL) and may be threat of survival due to metastasis to different sites of the body. The purpose of this present study mainly focused to assess QOL in patients suffering with metastatic breast cancer and its pharmaceutical management in a tertiary care hospital. QOL is a multidimensional model which includes physical, social, and psychological well-being of the patient. Physical symptoms of the disease, side effects of treatment, social and family support may influence QOL. Treatment for the metastatic breast cancer is majorly palliative therapy rather than curative i.e main goal is to managing the symptoms as opposed to prolonging life. So it is important for health care providers to consider treatment in terms of not only managing symptoms, but also stabilizing or improving other factors that affect QOL. Here in this study we used self-designed and validated questionnaire (which was taken from European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Breast Cancer {EORTC QLQ-BR23} and Functional Assessment of Cancer Therapy-Breast Cancer {FACT-B}) was used to assess the quality of life in metastatic breast cancer patients which consists of 30 closed ended questions which represents the difference between the past and present Health status of patient. Keywords: Metastatic breast cancer, QOL, EORTC-QLQ-BR23,FACT-B.

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