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TITLE:

THE GASTROINTESTINAL PRESENTATION IN ADULT MULTISYSTEM LANGERHANS CELL HISTIOCYTOSIS

AUTHORS:

Dr Tanzeelah Shamshad, Dr Shaista Qasim, Dr Sharjeel Hassan

ABSTRACT:

Langerhans cell histiocytosis is an uncommon histiocytic issue. The illness is restricted to one organ framework in around 55% of patients while the rest of with multisystem sickness. It is most normal in kids from one to three years of age. Be that as it may, his malady has been analyzed in all age gatherings. The LCH patients may shift in introduction relying on the destinations and degree of contribution. It is described by histiocyte penetration of the body organ. Most of gastrointestinal Langerhans cell histiocytosis is from pediatric cases. Gastrointestinal contribution of Langerhans cell histiocytosis is even rarer. This case is about a 69-year-old female which was presented in August 2018 at Mayo Hospital, Lahore. She was given endless loose bowels for a multi-month length, related to a critical weight reduction. Histopathological examination of the colonic mucosa affirmed Langerhans cell histiocytosis. Colonoscopy indicated mellow to direct pancolitis. Clinical examination and biochemical tests precluded thyrotoxicosis.

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