::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

TO KNOW THE CLINICAL EFFECT OF ORAL VITAMIN D3 SUPPLEMEN IN PATIENTS OF DIABETES MELLITUS TYPE 2

AUTHORS:

Dr Nek Daraz, Dr Usman Ali Younis, Dr Muhammad Usman Shakoor

ABSTRACT:

Background: To evaluate the clinical outcome of oral Vitamin D3 Supplementation in patients of Type 2 Diabetes Mellitus with generalized chronic adult Periodontitis. Study Design: This study was conducted in Dental Department of Mayo Hospital Lahore, for the duration of three months, from January 2020 to April 2020. Methods: A total of 92 patients, comprising 46 in non-diabetic and 46 in diabetic group were enrolled in the clinical trial according to the inclusion and exclusion criteria. Periodontal clinical parameter, Probing Pocket Depth (PPD) was assessed at baseline. Following initial examination Scaling and root planning was completed for all the subjects enrolled in the study and by cluster randomization first 25 patients from each group were supplemented with oral vitamin D3 granules of 60,000IU once a week for 8 weeks following SRP. At the end of the study after 8 weeks, Probing Pocket Depth was reassessed. Significant improvement was seen in both interventions namely SRP + VITAMIN D and SRP alone. But marked reduction in PPD was seen in SRP + vitamin D supplemented group. Reduction in PPD was more for Non diabetic patients when compared to Diabetic patients. Vitamin D supplementation can be used as an adjunct to SRP for both diabetic and non-diabetic patients with chronic periodontitis in vitamin D deficient subjects. Conclusion: Vitamin D supplementation has got a positive effect on periodontal health and it can be used as an adjunct to SRP in vitamin D deficient chronic periodontitis patients with and without type 2 diabetes mellitus. Keywords: Chronic periodontitis, type 2 diabetes mellitus, vitamin D supplementation, probing pocket depth.