- CODEN : IAJPBB
- issn 2349-7750
TITLE:
STUDY TO KNOW THE EFFICACY OF PRAZOSIN GIVEN ALONE OR IN COMBINATION FOR TREATING HYPERTENSION
AUTHORS:
Dr Liaqat Ali Shah, Dr Bakhtawar Zahra, Dr Syeda Dua Fatima
ABSTRACT:
Aim: This study was held to determine the efficacy of prazosin given alone or in combination with diuretic and with both diuretic and a Beta-adrenergic blocker to control the hypertension. Place and Duration: In the Medicine Unit I of Services Hospital Lahore for six months duration from September 2019 to March 2020. Methods: 130 cases of hypertension have been studied and treated with prazosin given alone or in combination with diuretic and with both diuretic and a Beta-adrenergic blocker to control the hypertension. The patients were observed for over one years. All these cases were clinically evaluated, a detailed medical history was collected and a comprehensive clinical examination, including fundoscopy, was performed. Blood pressure was recorded daily in the morning and afternoon, both in the supine position and for three days using a standard mercury sphygmomanometer, and standing blood pressure was recorded at least 2 minutes after getting up. The data was analyzed using SPSS Version 21.0. Results: Prazosin has been found to be a very safe and effective antihypertensive drug, either alone or in combination with a diuretic or beta-adrenergic drug with varying degrees of hypertension. The mean drop in blood pressure during standing position was 33 systolic and 22.30 diastolic. Side effects were mild and only 6 patients had to stop taking the drug. Prazosin has been found to be a very safe anti-hypertensive, especially in uremia and hypertension. Key Words: Prazosin, diuretic, Beta-adrenergic blocker, hypertension.
FULL TEXT
<Approved Journal
NLM ID:101711216 [Serial]
Included in EuroPub database
ICV 2015 - 61.16
Indexed In
S.J Impact Factor:7.157
cosmos Impact Factor:4.153
ICMJE Recommendations
IP Indexing Impact Factor: 2.76
Cover Page
