::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

TO KNOW THE DENGUE FEVER PREVALENCE WITH ITS CLINICAL AND HAEMATOLOGICAL FEATURES: AN OBSERVATIONAL STUDY

AUTHORS:

Dr Syeda Dua Fatima, Dr Bakhtawar Zahra, Dr Ahmed Shah

ABSTRACT:

Objective: To know the incidence of dengue as a cause of fever and to compare the haematological and clinical characteristics of dengue in proven and susceptible cases. Study design: An observational study. Place and Duration: In the Medicine department of Mayo Hospital Lahore for six months duration from August 2019 to February 2019. Methods: All patients older than 14 years of age who were treated in Services hospital for an acute febrile illness were assessed for dengue fever (DF) and haemorrhagic fever clinical features were noted. Dengue Shock Syndrome (DSS) and Dengue haemorrhagic fever (DHF) Patients with typical dengue fever clinical features (as stated by WHO) and haematological findings were evaluated in detail to compare possible and established cases of dengue fever. All acute febrile illness cases that did not show haematological abnormalities or clinical features of dengue fever were omitted. Laboratory and Clinical topographies were recorded in the SPSS 18.0 program and were identified as necessary for a statistical and descriptive analysis. Results: Of the 5200 febrile illness subjects, DF typical features were noted in 107 (2%) cases, dengue testing was done in 40/107 (37%), and most susceptible to have dengue in 67/107 (63%) cases. Of the cases tested with dengue, 38 were from DF and 2 were from DHF. The temperature of day 1 ranged from 99-1050 ° C (average 1010 ° C). Myalgia, 86 (80%), pharyngitis in 35%, headache in 54%, haemorrhagic symptoms in 2% and skin rash in 28% were observed. lymphadenopathy in 1, Hepatomegaly in 1 (0.5%) and in 12 (11.2%) splenomegaly was noted. Leukopenia (count <4x109 / L) was observed in 73%, platelet count <84% 109 / L, in 57% of cases ALT> 40 U / L was noted. Conclusion: The clinically suspected dengue virus infection frequency was (2%) 107 cases, of 5200, 40 (0.8%) dengue fever cases were proven. Shivering and chills, , headache, body ache, rash, myalgia, haemorrhagic symptoms, total white blood cell count, platelet count, and ALT and fever are parameters for detecting suspected dengue virus infection; The diagnosis cannot be established lest reinforced by dengue-specific IgM or molecular studies. Keywords: Dengue haemorrhagic fever (DHF), Dengue fever (DF), Administration, Dengue Shock Syndrome (DSS).