Bhuvanesh R. Thakare*
The main focus of our article is that benefits and pitfalls of corticosteroid. Dexamethasone is the steroid drug which classify in corticosteroid class. It was introduced for medical use in 1958 which relieves inflammation in various part of body. Now a day there is worst situation in world about covid-19 pandemic. Whole world suffered from covid-19 pandemic. In this situation government of all countries are busy in discovery of vaccines. Many drugs are used in trial of prevent corona virus. Dexamethasone is the drug is also used in this situation. Use of this drug is benefits in some patients but side effect of this drug is more to knows and its harm to patients. That’s why Food and Drug Administration (FDA) does not approve trial of Dexamethasone in covid-19 disease. The present article tells us the significance of drug repurposing, Mechanism of action of Dexamethasone against covid-19, Trial report of Dexamethasone about improve survival rate in covid patients which receiving oxygen or on a ventilation. Key words: Corticosteroid, Dexamethasone, Drug repurposing, Covid-19, Inflammation, FDA, Ventilation.