::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

CONGENITAL MALFORMATION IN SINGLETON PREGNANCIES COMPLICATED WITH POLYHYDRAMNIOS

AUTHORS:

Dr. Sara Fazal, Dr. Rameesha Shafiq, Dr. Maida Naeem

ABSTRACT:

Introduction: Polyhydramnios is the term used to describe an excess accumulation of amniotic fluid. This clinical condition is associated with a high risk of poor pregnancy outcomes. Objectives: The main objective of the study is to analyse the congenital malformation in singleton pregnancies complicated with polyhydramnios. Material and methods: This descriptive study was conducted in Holy Family/Benazir Bhutto Hospital, Rawalpindi during April 2019 to January 2020. A proper history, general physical examination, and routine investigation were carried out. Women who were included having childbearing age 18 –42 years, women should be a diagnosed case of polyhydramnios on ultrasound (Amniotic fluid>25cm;vertical pocket liquor >8cm, gestational age should be between 28 –37 weeks (on history taking) and patients of polyhydramnios with and without associated congenital anomalies. Results: There were 39 pregnant ladies with amniotic fluid index (AFI) of >25cm during the study period. One of the pregnant lady with history of cardiac disease was excluded from the study. A total of 38 pregnant ladies with polyhydramnios were included for statistical analysis. Mean age of the pregnant ladies was 28.8±6.3 years. Polyhydramnios was categorized as mild (AFI: 25.1-30 cm), moderate (AFI: 30.1-35 cm) and severe (AFI >35 cm). Out of 38 pregnant ladies, 71.1 % had mild polyhydramnios. Conclusion: It is concluded that it is very important to recognize polyhydramnios, because of its contribution to the development of malformations in the fetus. Further studies are needed to check the impact of the severity of polyhydramnios on congenital malformations.