Dr Arfah Shahid, Dr Muhammad Nawaz Aslam, Dr Ufaq Naseem
Introduction: Sleep blood pressure (BP) is a powerful predictor of cardiovascular complications, and there is suggestive evidence that controlling BP during sleep has beneficial outcomes. When drugs are given in the morning, the drug concentration may be lowest at the time when good BP control is desirable. Objectives of the study: Our main objective is to find the correct time of medication either it would be morning or evening. Methodology of the study: This cross-sectional study was conducted at Rawalpindi Medical University, during June 2019 to January 2020. This study was conducted according to the rules and regulations of ethical committee of hospital. This research will help towards next findings of effect of blood pressure in hypertension and its responsible factors. Results: In the present study, the numerical falls in sleep (night-time) SBP and DBP at all time periods presented were greater than the daytime fall on both the morning, and night-time dose of valsartan and on lisinopril, though there is no statistical analysis of this effect. Conclusion: It is concluded that there are several factors which are responsible of elevation and decreasing blood pressure but that is required to clarify the advice to give to the treating physician is one in which the medication is given when awake or in the evening, and medication is titrated by usual clinic BP. The result needs to be monitored by 24-h BP measurements to determine which strategy is most effective in achieving optimal control.