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TITLE:

WEIGHT CHANGES DURING TUBERCULOSIS TREATMENT-IMPACT OF AGE, GENDER AND SITE OF TUBERCULOSIS-SINGLE CENTER STUDY.

AUTHORS:

Dr Javed Iqbal, Hamza Rafique Khan, Muhammad Shahbaz, Waqas Lateef,Dr Shahnawaz, Dr Aqib

ABSTRACT:

Objective: This study was conducted to document effect on body weight during of antituberculous therapy with impact of site of tuberculosis, age and gender of patient. Study Design: Cross sectional study Place & Duration: At Chest unit Bahawal Victoria Hospital Bahawalpur between November 2018 to April 2019 Methodology: The weight record was documented at start, first, second, fifth month and completion with age, gender and site of disease. Results: Eighty-four patients enrolled. Body weight at the start of treatment was Range 25-90Kg (Mean 48.22+/-12.17) and at completion of treatment Range 28-89 Kg (Mean 52+/-12.31) . [ Pulmonary Weight change P- (0.042) ] and Body weight after first month of treatment is Range 26-92 Kg (Mean 48.80+/-12.26) [Pulmonary Weight change P- (0.000) ] - Body weight after second month of treatment is Range 26-92.52 Kg (Mean 49.70+/-12.08) and Body weight after fifth month of treatment was Range 27-90 Kg (Mean 50.91+/-12.11) The gender-based P Value for 1st Month weight Change Male - 0.016 Female- 0.000 and P Value At ATT completion weight Change Male - 0.224 Female- 0.011. The weight changes in different sites with age were non-significant P>.05, for all recorded months. Conclusion: Significant weight gain was seen in pulmonary tuberculosis and first month weight gain was statistically significant in both genders. Age related body weight changes were non-significant. Keyword: Tuberculosis, Weight , Body, Gender, Age, Site of tuberculosis.

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