Dr Raina Amin, Dr Muhammad Awais, Dr Ruqaya Bashir.
The prevalence of chronic atrophic gastritis is obscure as it is found that most of the patients of atrophic gastritis are usually anticipated with progressive phases of disease while at early phases diagnosis is uncommon. The demolition of parietal cells, may be autoimmune directed or outcome of H. Pylori infection, establish a decreased in the secretion of acid. The threat of neuroendocrine tumor development increases with enhanced levels of gastrin in serum originated by Hypo/achlorhydria. The fate of pernicious and megaloblastic anemia occurrence connected with persistent development hypochromic and microcytic anemia. Furthermore, a high level of homocysteine may be by depletion of cobalamin, with an elevated risk to develop CVD and might have a connection with neurological indications, basically atrophy, and demyelinated spinal cord recognition build the abnormal sensory-motor. Gastrointestinal manifestations are related to non-acid reflux.