::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

SEROLOGICAL IMMUNOCHROMATOGRAPHIC METHOD IN THERAPY WITH SARS-COV-2 POSITIVE CORONAVIRUS PATIENTS

AUTHORS:

Muhammad Hassan Naeem Goraya, Dr. Usman Asim Malik, Dr. Hira Umar

ABSTRACT:

An episode of novel coronavirus Covid-19 was happened in south and centre, Pakistan and quickly blowout to different urban areas and countries. The standard indicative methodology that broadly embraced in center is nucleic corrosive recognition by constant RT-PCR. Notwithstanding, bogus negative pace of strategy is unneglectable also serological techniques are desperately justified. Now, authors introduced the colloidal gold-grounded immunochromatographic strip focusing on viral IgM or IgG neutralizer and contrasted it and continuous RT-PCR. The affectability of ICG examine through IgM and IgG combinatorial identification in nucleic corrosive affirmed respondents were 13.2%, 94.6% and 97.9% at the beginning phase (1–7 days after beginning), transitional stage (9–16 days after on-set), and late stage (over 17 days), individually. The ICG location limit in nucleic corrosive negative speculated cases was 45.7%. Our current research was conducted at Jinnah Hospital, Lahore from March 8, 2020 to May 19, 2020. Likewise, concordance of entire blood tests and plasma indicated Cohen's kappa estimation of 0.95, which spoke to the practically ideal understanding amongst 4 kinds of tests. All in all, serological ICG strip measure in recognizing SARS-CoV-2 disease is mutually delicate and reliable, which is measured as a magnificent strengthening method in medical application. Keywords: Serological Immunochromatographic, SARS-COV-2, Corona Virus Positive.