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EFFICAY OF PHLOROGLUCINOL IN COMPARISON TO THE PLACEBO AT THE FIRST ACTIVE STAGE OF LABOUR

Muhammad Usman Rasheed, Dr. Muhammad Azfar Maqsood, Hira Tariq Chaudhary

Objectives: The objective of this research is the comparison of phloroglucinol to placebo in terms of mean duration of active first-stage of labour. Materials & Methods: The study included sixty singletons pregnant patients having first-stage of uncomplicated labour, of (18 – 40) age group. Obstetrical/surgical complications, multiple pregnancies, heart-rhythm abnormality, asthma, and heart failure was the study’s exclusion criteria. Patients were divided into group A of spasfon/phloroglucinol and B of placebo randomly through lottery method. Then we noted the time (in minutes) of first-stage labour from (3 – 4) cm cervical dilatation having uterine contractions as regular in order to complete cervical dilation (10 cm) and descent of fetal part presentation. Results: The mean age was (27.2±5.2) and 26.8±5.4 years among the patients of group A and B respectively. Mean gestational age was 38.3±1.4 and 38.5±1.3 weeks among the patients of group A and B respectively. The mean duration of first-stage labour was 230.2±52.9 and 345.3±50.5 minutes among the patients of group A (Phloroglucinol) and group B (Placebo) with p-value <0.0001. Conclusion: The study concludes that Phloroglucinol is comparatively more effective in the reduction of the duration of first-stage (active) labour than placebo and is recommended for the acceleration of labour among such concerned patients. Keywords: Neonatal, Parous Women, Cervical Effacement, Analgesics, Labour, Contractility

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