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A COMPREHENSIVE STUDY ON EFFICACY OF RECTAL INDOMETHACIN IN PREVENTION OF PANCREATITIS

Dr. Muhammad Asad Abdullah, Dr. Noor-us-Syyam Sumra, Dr. Khalid Nawaz

Introduction: Endoscopic Retrograde Pancreatocholangiography (ERCP) is one of the most commonly performed, most complex and high risk endoscopic procedure performed for the treatment of various conditions of biliary and pancreatic ductal system. Aims and objectives: The objective of this study is to find the efficacy of rectal indomethacin in prevention of pancreatitis. Methodology of the study: This study was conducted at Bahawal Victoria hospital, Bahawalpur during Nov 2017 to April 2018. There were 100 patients which were selected for this study. Patients divided into two groups. One group (50 patients) was given per rectal indomethacin while other group (50 patients) given no suppositories. Results: Age distribution of the patients was done, it shows that 30%(n=45) in Indomethacin and 29.33%(n=44) without Indomethacin group were between 15-50 years of age while 70%(n=105) in Indomethacin and 70.67%(n=106) without Indomethacin group were between 51-85 years of age, mean+sd was calculated as 56.28+8.39 and 55.72+7.84 years in both groups respectively. Conclusion: It is concluded that the frequency of Post ERCP Pancreatitis is significantly lower in patients treated with rectal indomethacin when compared to those without it.

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