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PREVALENCE AND ETIOLOGY OF HEPATITIS E (HEV) INFECTION AMONG PATIENTS ADMITTED IN MEDICINE DEPARTMENT

Dr. Tayyaba Malik, Dr. Sohail Iqbal, Dr. Rida Muhammad Ashraf

Purpose: To Know the viral causes of patients with acute hepatitis E in medical unit and evaluates hospital stay in HEV patients. Study Design: Hospital based an Observational Study. Place and Duration: In Medical Unit I of Services Hospital Lahore for one year period from July 2017 to July 2018. Methodology: Diagnosis was established with ALT more than ten times the normal range (400 uu / ml). Acute hepatitis was labeled and its etiology was established for HCV-IgM and HEV-IgM, HAV-IgM, HBV-IgM by ELISA technique. In female patients, appropriate pregnancy history / abortion were obtained and pregnancy test with a gynecologist confirmed with prenatal ultrasound and consultation. Results: 113 patients with acute hepatitis were examined during the study. Of these, 61 patients had definite viral etiology. Of these 61 patients, 27 were HEV, 7 were HBV, 13 were HAV and 14 were HCV. Of 27 patients with HEV, 22 were male and 5 were female. There was no history of pregnancy or previous abortion in all female patients. Conclusion: HEV-induced acute hepatitis is more common than HAV in labours. Improvement in patients with acute hepatitis infected with HEV is almost the same as in other viral etiologies. Key words: HBV, hepatitis C virus, hepatitis A virus.

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