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TITLE:

PREVELANCE OF DAWN PHENOMENON AND SOMOGYI EFFECT IN DIABETIC PATIENTS

AUTHORS:

Dr. Adnan Sharif, Dr. Hasan Amin, Dr. Masooma Batool Ghauri

ABSTRACT:

Patient with diabetes mellitus may have morning hyperglycemia despite of management due to somogyi effect and dawn phenomenon. Occurrence of dawn phenomenon is due to relative deficiency of insulin during the night time when insulin antagonist harmones are rising, so patient experience morning hyperglycemia and hypeglycemia at midnight as well. Somogyi effect occurs due to relative insulin excess which causes midnight hypoglycemia and subsequent morning hyperglycemia due to effects of reactionary raised insulin antagonizing harmones. In this study, 41(21%) out of 200 selected diabetic patients were having morning hypoglycemia despite of insulin therapy. 8(19%) were experiencing it due to somogyi effect and remaining 34(81%) due to dawn phenomenon. Strict glycemic control is essential to prevent complications of diabetes mellitus. Hence, these morning hyperglycemic patients must be screened and their insulin regimen adjusted accordingly.

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