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VARIOUS MODES OF CLEIAC DISEASE PRESENTATION IN CHILDREN OF 3-15 YEARS OF AGE

Dr. Rida Saghir, Dr. Madiha Sammer, Dr. Izza Khalid

Objective: To evaluate the celiac disease clinical presentation and the effect on clinical symptoms after giving of gluten-free diet in children aged 3-15 years. Study Design: An Observational descriptive study. Location and Duration: In the Pediatric Department of Services Hospital, Lahore for one year duration from July 2017 to July 2018. Methods: A total of 150 cases that met the inclusion criteria were randomly selected. Proximal bowel biopsy and Immunological assay were done in all cases. The results were analyzed and explained in the proforma. Results: The main complaints were lack of growth (81.07%) and diarrhea (78.93%). The main signs were short stature (88%) and anemia (72%). The typical biopsy findings were observed in all subjects. Most of the proven biopsy patients responded to a gluten-free diet (79%) and showed a significant correction in laboratory and clinical parameters. Conclusion: The growth parameters and diarrhea improved significantly after treatment with a gradual reduction in anti tissue transglutaminase and serum antigliadin. Patients who did not fit adequately were mostly adolescence. Key words: development, celiac disease, gluten

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