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DIAGNOSTIC ACCURACY OF MRI IN PREDICTING SOFT TISSUE MALIGNANCY OF MUSCULOSKELETAL SYSTEM BY TAKING HISTOPATHOLOGY AS GOLD STANDARD

Dr. Saeeda, Dr. Mohammad Tahir, Dr. Hassan Bukhari

Background: Soft Tissue Malignancies of Musculoskeletal System or sarcomas are a rare and heterogeneous group of malignant tumors of mesenchymal origin that comprise less than 1 percent of all adult malignancies and 12 percent of pediatric cancers. MR imaging is an integral part of the multi-modality approach to the assessment of malignancies of soft tissue musculoskeletal system diagnosis and treatment. Objective: The objective of the study was to evaluate the diagnostic accuracy of MRI in predicting soft tissue malignancy of musculoskeletal system by taking histopathology as gold standard. Study Design: Cross sectional (validation) study Sampling Technique: Non probability consecutive sampling Setting: Department of Radiology and Medical Imaging Allied Hospital Faisalabad. Duration of Study: 09 months after the approval of synopsis. From: 01-04-2016 to 31-12-2016 Results: In our study, mean age was calculated as 50.21+7.03 years, 48.35%(n=44) were male and 51.65%(n=47) were females, the diagnostic accuracy of mri in predicting soft tissue malignancy of musculoskeletal system by taking histopathology as gold standard shows 85.29% sensitivity, 87.72% specificity, 80.55% positive predictive value, 90.91% negative predictive value and accuracy rate was calculated as 86.81%. Conclusion: We concluded that the diagnostic accuracy of MRI is encouraging for predicting soft tissue malignancy of musculoskeletal system by taking histopathology as gold standard. Keywords: Soft Tissue Malignancy of Musculoskeletal System, MRI, Diagnostic Accuracy

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