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TITLE:

STUDY TO KNOW THE ASSOCIATION OF IMPAIRED GLUCOSE TOLERANCE TEST WITH FIRST DEGREE RELATIVES OF DIABETICS

AUTHORS:

1Dr. Sania Khan, 2Dr. Ayesha Huma, 3Dr. Syeda Saba Sohail

ABSTRACT:

Diabetes is linked with advanced age, obesity, diabetes family history, physical inactivity and so on. It is the most frequently associated disease. Genetic factors interact with environmental factors and are complex. Impaired glucose tolerance is also proved as a risk factor. Objective: The purpose of this analysis was to determine the association of impaired glucose tolerance with diabetes in first degree relatives. Study Design: An experimental observational Study. Place and Duration: In the Medicine Unit II of Holy Family Hospital Rawalpindi for six months duration from January 2018 to June 2018. Methods: Fifty first-degree diabetic patients of both sexes were included in the study as experimental volunteers. The patients were divided into three groups according to their age, ie, ages ranging from 14 to 25 years, with a range of ages ranging from 26 to 35 years and with a group of 26-35 years and from 36 to 50 years. Results: BMIs of the first-degree relatives of males in the 14-25 age group were increased significantly (P <0.01) contrast to the controls, with ages ranging from 26 to 35 years the first degree relatives BMI did not increase significantly compared to the group of control (P> 0.06), and the BMI of the first-degree relatives of the males in the 36-50 age group was higher than the control group showed a very obvious variation (P <0.01). Conclusion: GTT increased in the age group (14-25) in the first-degree relatives of diabetes in contrast to the control group, but vast difference was observed in fasting and GTT in 1 hour (P <0.01). BMI with ages between 26-35 showed a significant change after ½ h of blood glucose sample. In the 35-50 age groups, there is a significant change in fasting blood sugar in BMI. Key words: glucose tolerance test, first degree relatives, diabetes, BMI.

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