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OVERVIEW OF LIVER FAILURE, COMPLICATIONS AND THERAPEUTIC APPROACHES

Mohammed Ahmed A. Alamari, Saleh Mohammad S. Alqahtani, Abdulelah Mohammed Ahmed Abusabah, .Hamad Mohammed Ahmed Abusebah, Mohamed Ayed Al sehmah, Mohammed Awadh S Alqahtani, Ali Salem S Al Mannaa, Ali Ahmed Bajafar, Ibrahim Hassan M. Almousaedi,Ahlam Falah M. Alotaibi, Weaam Ahmed H Al-Manea, Enas Abdulkarim Alkhoutani

Cerebral oedema, infection and multi-organ failure are the most common causes of death in ALF. Chronic liver disease (CLD) results in significant morbidity and death, mainly due to issues [hepatic encephalopathy, ascites, hepatorenal syndrome (HRS) and esophageal variceal hemorrhage (EVH)]. Management, for that reason, must intend to stop these complications to permit the liver to regrow or, if this is not likely, to allow adequate time to identify an appropriate organ for transplant. Computerized search was performed using following databases; CENTRAL, PUBMED, MEDLINE, and EMBASE. for all published studies concerning Lichen Planus up to 2018. Using the term ‘‘liver failure. Death of ALF is still unacceptably high. Although considerable progress has actually been made in the understanding of the pathophysiology of ALF, clinical trials are limited. Liver transplantation is the best treatment for a high proportion of ALF patients. In order to maximize the results of liver transplant, approaches of connecting are under growth. Modest hypothermia is a major enhancement to the arsenal, enabling patients with serious, uncontrolled intracranial high blood pressure to be linked successfully to transplant.

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