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TITLE:

EVALUATION OF RECENT UPDATES REGARDING POST- MENOPAUSAL MANAGEMENT

AUTHORS:

Dhafer Mubarak Alajmi, Mohammed Abdullah Sharif, Ahmad Fuad Malaekah, Mohammed Anwar Albinissa, Omar Obaidalluh Althobaiti, Omer shamim Mohammad Yahya Bari, Selwan Yaslam Bazuhair, Shahad Khalid Aljifry, Haneen Abdullah Alqubali, Moroj Fadol Alreheli, Naseem Ahmad Matari

ABSTRACT:

Background: Osteoporosis is a skeletal disorder characterized by low bone mineral density that increases fracture risk. The prevalence of osteoporosis is expected to increase even further due to the reported increase of life expectancy worldwide and the costs of osteoporotic fracture–related morbidity and mortality are going to burden the healthcare system. Optimization of bone health throughout life can help prevent osteoporosis and its consequences. Many studies have been published in order to examine osteoporosis management strategies and their efficacy. Objective: A lot of literature have been done in order to provide a better outcomes for patients presented with postmenopausal osteoporosis, in our review we aim to discuss the recent literature that discussed the recent updates regarding its management. Method: PubMed database were used for articles selection. All relevant articles related to our review were chosen to cover the following topics: Osteoporosis, Post-menopausal, Management and Diagnosis. We excluded other articles, which are not related to our objectives. The data have been extracted according to specific form to be reviewed by the authors. Conclusion: The mainstay of prevention and treatment of postmenopausal osteoporosis is estrogen replacement therapy. In addition, increasing calcium intake and vitamin D is needed for bone growth and bone remodeling by osteoblasts and osteoclasts. Bisphosphonates are the most used anti-resorptive agents in the world for the treatment of osteoporosis and are in use for three decades. The most known anabolic therapy is PTH. Regarding prevention, exercise has the potential to be a safe and effective way to avert bone loss in postmenopausal women

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