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DETECTION OF THE AXILLARY LYMPH NODE METASTASES AMONG PATIENTS SUFFERING FROM BREAST CARCINOMA UTILIZING BLUE DYE

Dr Abdul Ghaffar Arain, Dr Madiha Shoaib, Dr Raja Muaaz Ahmad

Objective: The aim of this study is to find out the diagnostic preciseness of the Methylene Blue Dye to identify the lymph node metastases among patients suffering from breast carcinoma by utilizing the gold standard of histopathology. Methodology: This was a quasi-experimental research work conducted at Civil Hospital Karachi from March 2016 to December 2018. Ethical committee of the institute gave the permission to conduct this research work. Total eighty-five patients with confirmed carcinoma with biopsy were the part of this research work. We infiltrated the 1.0% methylene blue dye in the peritumoral region of the infected breast. We called the blue stained node as the sentinel lymph node which came under recognition and we meticulously dissected it out. We send the sentinel lymph node and mastectomy with the sample of axillary clearance for histopathology in 2 different bottles and then we carried out the comparison of the histopathology report. Results: There were positive Axillary Lymph Nodes for carcinoma in sixty-one patients (71.70%) out of total 85. Total 2 patients were present with the negative sentinel lymph node while having positive non-sentinel lymph node (false-negative). In 3 patients of this research work, there was only involvement of sentinel lymph node but there was no involvement of axilla (False-positive). The preciseness, sensitivity and specificity were 94.10%, 96.8% and 86.36% correspondingly. Conclusion: Methylene Blue Dye approach is very credible and secure identification modality for the identification of the sentinel lymph node in the patients suffering from breast carcinoma due to its high preciseness. Keywords: Breast Carcinoma, Sentinel Lymph Node, Methylene Blue Dye, Preciseness, Meticulously, Sensitivity, Specificity, Nodes.

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