ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

LEVEL OF HEMOCYSTEINE IN PATIETNS OF TYPE-2 DIABETES AND ITS ASSOCIATION WITH BLOOD PRESSURE, LEVELS OF HBA1c AND DIABETES DURATION

Dr Adnan Abbas Nizami, Dr Bilal Ahsan, Dr Usama Ahmed Bakhtiari

Objective: The aim of this study research work aimed to find out the levels of homocysteine in the patients of Tpe-2 diabetes and its association with the levels of HbA1, body mass index, Blood Pressure and total diabetes duration. Methodology: This was a transverse research work carried out in DHQ Hospital Mianwali in a period of seven months from August 2018 to February 2019. We collected the data and used SPSS V.20 for the analysis of the collected information for the statistical analysis of that data. Correlation test of Bivariate Pearson was in use for the determination of the comparison between homocysteine and body mass index, systolic blood pressure and diabetes duration. Results: There were total 125 patients in this research work in which 68.0% were female and 32.0% were male patients with an average age of 51.450 ± 8.37 years of age. The average body mass index of the patients was 28.71 ± 4.75, average systolic BP was 130.0 ± 20.98 mmHg, the average diastolic BP was 83.360 ± 11.280 mmHg and the average diabetes duration of the patients was 7.01 ± 6.180 years. We found a strong association between the systolic BP and diabetes duration with the level of homocysteine. There was no significant association of the level of homocysteine with the body mass index and HbA1c. Conclusion: There was a positive association of systolic BP and diabetes duration with the level of homocysteine. There was no strong association between homocysteine with the level of HbA1c and there is need of further research works on large size of samples and for greater duration to reach an assertive conclusion about the association between these 2 variables. Keywords: Cardiovascular, Homocysteine, Body Mass Index, Diabetes, Hba1c, Insulin, Diastolic.

FULL TEXT