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TITLE:

ANALYSIS OF LEVEL OF ANTIOXIDANTS IN THE DEVELOPMENT OF DIABETES MELLITUS IN PAKISTAN

AUTHORS:

Muhammad Moeen Khan, Zainab Asim, Syed Kamal Husnain Shah

ABSTRACT:

The main objective of our study is to find the role of antioxidants and measure the level of oxidative stress and their role in the development of diabetes. This cross sectional study was conducted at District Headquarter Hospital, Nankana Sahib during February 2019 to August 2019. For this purpose we selected the patients who was suffering from a common disease diabetes. This study is based on the local population of Pakistan, which shows the stress level in Pakistani environment. According to analysis of data level of antioxidant and oxidative stress is increasing in diabetic patients because cell become destroyed. GSH is important non-enzymatic antioxidant which helps in scavenging of free radical mechanism. It is concluded that level of antioxidants in our body plays an important role. It is obvious from the presented data that a relation exists between hyperglycaemia, oxidative stress, cellular and endothelial dysfunction.

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