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CORRELATION OF INTRA OCULAR PRESSURE WITH SERUM ELECTROLYTES IN HYPERTENSIVE AND NON-HYPERTENSIVE PATIENTS

Dr Rehab Habib, Dr Rana Mohammad Mohsin Javed, Dr Farhat Ijaz, Dr Rana Khurram Aftab, Dr Hira Sohail, Dr Mussarat Ijaz

Hypertension is a common medical disease which affects population all over the world including Pakistan. Crisis in raised blood pressure accounts for about one fourth of all medical emergencies. Higher blood pressure is the main independent determinant of higher intraocular pressure. Electrolytes play an important role in hypertension. Therefore we conducted this study to compare serum levels of sodium, potassium and chloride in hypertensive and non-hypertensive patients and find out their correlation with Intraocular pressure at tertiary care hospital of Lahore. Material and methods: We conducted this study at Mayo Hospital Lahore & 108 subjects were enrolled in our study who were divided in 2 groups having 54 subjects in each group. Written Informed written permission was taken. Blood pressure was determined by mercuric sphygmomanometer while IOP was assessed by Goldmann applanation tonometer by using 2 % fluorescein strips. 5ml of blood sample was drawn to determine the level of serum electrolytes. Results: In our study mean age of patients with hypertension was 56.37±6.71 years and non-hypertensive patients were 52.35±5.92 years. IOP was significantly higher in right and left eye in hypertensive patients (p<0.001). Serum Na+ level was significantly higher while K+ was significantly lower in hypertensive subjects (p<0.001). Mean serum Cl- was lower in hypertensive though not significant. Conclusion: We concluded that hypertensive patients had significantly higher levels of serum sodium while we found significant lower levels of serum potassium & chloride. We found a positive correlation between serum electrolytes and intra ocular pressure. Raise in serum sodium is directly related to increased blood pressure which in turn raises the intra ocular pressure Keywords: Hypertension, IOP, Na+, K+

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