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TITLE:

DIAGNOSTIC ACCURACY OF COMPUTED TOMOGRAPHY FOR ACUTE APPENDICITIS KEEPING HISTOPATHOLOGY AS A GOLD STANDARD

AUTHORS:

Dr. Yadullah, Dr. Junaid Arshad, Dr. Hassan Majeed

ABSTRACT:

Aim: To determine diagnostic accuracy of computed tomography in the diagnosis of acute appendicitis keeping histopathology as a gold standard. Study Design: A Cross Sectional study. Place and duration: In the Department of Radiology, Khyber Teaching Hospital, Peshawar for six months duration from Methods: A total of 191 patients suspected of having acute appendicitis were included in the study by a non probability consecutive sampling technique and subjected to CT pre-operatively and histopathology post operatively for the acute appendicitis. Results: The mean age of the patients was 29.5 + 6.7 years. We had 53.4% males & 46.6% females. On CT we observed that the acute appendicitis was recorded in 58.1% of patients compared to 47.6% on histopathology. On applying the formulae for calculation, sensitivity of CT was found to be 89% and specificity 70%. The positive predictive value of the CT is 72.9% and negative predictive value is 87.5%. Conclusion: CT is a highly sensitive and specific tool for the detection of acute appendicitis. As such, it is a useful radiological marker for diagnosis of acute appendicitis in adults and further studies are recommended to confirm its usefulness. Keywords: Acute appendicitis, computed tomography, total leucocyte count, ultrasound, histopathology

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