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COMPARISON OF BIOCHEMICAL AND CLINICAL PROFILE BETWEEN GERIATRIC AND NON- GERIATRIC PATIENTS WITH CHRONIC KIDNEY DISEASE

Dr. Qadeer Ahmed Tariq, Dr. Khalid Khan, Dr. Sameeulah Khan, Muhammad Asad Qadeer

Objective: To compare biochemical and clinical profile between geriatric and non- geriatric patients with chronic kidney disease. Material and methods: This cross sectional study was conducted at Department of Urology, Sahiwal Medical College, Sahiwal from January 2018 to December 2018 over the period of 1 years. Total 100 patients of chronic kidney disease (50 elderly patients and 50 non-elderly patients) were selected and biochemical and clinical profile between both groups was compared. Results: Total 100 patients of chronic kidney disease (50 geriatric and 50 non- geriatric) were selected. Mean age of geriatric patients was 62.74 ± 3.43 years and mean age of non-geriatric patients was 48.56 ± 5.88 years. Most common clinical sign symptom was general weakness 50 (100%) and 50 (100%) in both groups followed by pedal edema in 42 (84%) patients in geriatric patients in 32 (64%) non- geriatric patients, oliguria in 38 (76%) geriatric patients in 32 (64%) non- geriatric patients. Statistically significant difference was observed for levels of blood urea (p=0.0054), serum sodium (p=0.0231), total protein (p=0.0078), SGOT (serum glutamic-oxaloacetic transaminase) (p=0.0002), SGPT (serum glutamic pyruvic transaminase) (p=0.0089), Triglyceride (p=0.084), haemoglobin (p=0.0014) and MCV (p=0.033) Conclusion: Results of present study showed that elderly chronic kidney disease patients are more likely to be develop hyponatremia, hypertriglyceridemia and anaemia, amongst mentioned abnormalities. Understanding the biochemical abnormalities beforehand helps in appropriate risk assessment as well as modifications in patient management. Key words: Chronic kidney disease, lipid profile, geriatric, end-stage renal disease

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