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ANALYSIS OF ROLE OF IL10RA GENE IN GENETIC POLYMORPHISMS IN LEUKEMIA PATIENTS

Hajira Zainab, Iqra Asif, Hifza Fatima

The main objective of this study is to find the correlation of genetic polymorphisms in IL10RA which modify the association of blood transfusion and induce apoptosis of human leukemia. This descriptive study was conducted in Hina Hospital, Lahore during March 2019 to October 2019. There was no violence of rules and regulations of authority. All histologically confirmed cases of leukemia diagnosed from 2015 to 2016 in a hospital. Our results suggested that there is no positive correlation between IL10RA and leukemia disease. Our results suggest that genetic polymorphism in IL10RA gene modifies the association between blood transfusion and risk of leukemia B-cells.

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