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FINE NEEDLE ASPIRATION CYTOLOGY OF BREAST LUMPS WITH HISTOPATHOLOGIC CORRELATION

Dr. Iftikhar Ahmed Bhatti, Dr. Fawad Hameed, Dr. Ali Gohar Khan

Objective: To assess the fine needle aspiration cytology of breast lumps with histopathologic correlation. Material and methods: This cross sectional study was conducted at the Department of Surgery, Sharif Medical & Dental College Lahore from July 2018 to December 2018 over the period of 6 months. Total 100 clinically diagnosed female with breast lump having age 20-60 years were recruited for this study. Diagnostic accuracy of fine needle aspiration cytology (FNAC) in selected patients was assessed by using histopathology as gold standard. Results: Total 100 females with breast lump was selected. Mean age of the Female patients was 36.15 ± 9.75 years. Histopathological diagnosis of breast lesions showed 28 (28%) malignant and 72 (72%) benign cases. True positive (TP) were recorded as 25 (25%), 9(9%) false positive (FP), 5(5%) false negative (FN) and 68(68%) as true negative (TN), sensitivity was 83.33 %, specificity was 87.14%, positive predictive value (PPV) was 73.53% and negative predictive value (NPV) was 92.42%. Conclusion: The evaluation of diagnostic accuracy of fine needle aspiration cytology in a breast lump using histopathology as gold standard shows a greater sensitivity and specificity, less invasive and cost effective procedure for the diagnosis. Key Words: Diagnostic accuracy, breast lump, fine needle aspiration cytology

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